Posts Tagged ‘diabetes’

Sabine Vollmer

RTP Wrapup 2/26

Friday, February 26, 2010, 12:22 am By No Comments | Post a Comment

A Senate committee report blasts GlaxoSmithKline for being more concerned about the sales of Avandia than about possible serious cardiovascular risks associated with the blockbuster diabetes pill. Also, two Research Triangle area companies developing new drugs sign deals.

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Sabine Vollmer

Digging for the roots of diabetes

Wednesday, December 9, 2009, 7:58 pm By No Comments | Post a Comment

Every year, the number of Americans with diabetes rises by about 1 million and genetic risk factors alone can be blamed for only a small portion of the cases. The 30 to 35 known diabetes genes, as researchers have dubbed them, account for only about 10 percent of the risk that a brother or sister of a diabetic will also develop the disease.

Dr. Ronald Kahn

Dr. Ronald Kahn

To better understand the other 90 percent, said Dr. Ronald Kahn, a Harvard University medical professor and vice chairman of the Joslin Diabetes Center, “we have to look at the environment.” Read more…

Sabine Vollmer

RTP Weekahead 12/7

Sunday, December 6, 2009, 11:36 pm By No Comments | Post a Comment

Events taking place the week of Dec. 7 in the Research Triangle area that are open to the public:

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Sabine Vollmer

Next: A crucial decision

Thursday, September 3, 2009, 8:23 am By 1 Comment | Post a Comment

This is the last part. Continued from part 2.

Developing medicines is a minefield that Tranzyme Pharma has navigated well so far. But the Durham company is about to embark on one of its trickiest missions.

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Sabine Vollmer

Getting a ghrelin drug to market

Thursday, September 3, 2009, 8:20 am By No Comments | Post a Comment

This is the second part of three. Continued from part 1.

Work on promising ghrelin medicines has gotten to a critical stage a decade after Japanese researchers discovered the hormone that stimulates hunger and is linked to insulin production.

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Sabine Vollmer

Ghrelin: A new hormone is found

Thursday, September 3, 2009, 8:15 am By No Comments | Post a Comment

INTRODUCTION

Tranzyme Pharma is one of dozens of drug development companies in North Carolina’s Research Triangle area, a biotech hot spot that is ranked third in the nation by number of companies. The Durham company has diligently advanced therapies based on a hormone that was discovered a decade ago, a technology also used by two rivals. Now, Tranzyme’s Board of Directors has to decide how to pay for the final development step and get its drugs to market: Go public, sell the company or go back to its investors hat in hand one more time.

This is the first part of three.

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Sabine Vollmer

Next: A crucial decision

Tuesday, July 28, 2009, 9:14 am By No Comments | Post a Comment

This is the last part. Continued from part 2.

Developing medicines is a minefield that Tranzyme Pharma has navigated well so far. But the Durham company is about to embark on one of its trickiest missions.

Read more…

Sabine Vollmer

Getting a ghrelin drug to market

Tuesday, July 14, 2009, 11:38 am By No Comments | Post a Comment

This is the second part of three. Continued from part 1.

Work on promising ghrelin medicines has gotten to a critical stage a decade after Japanese researchers discovered the hormone that stimulates hunger and is linked to insulin production.

Read more…

Sabine Vollmer

Ghrelin: A new hormone is found

Monday, July 6, 2009, 9:24 am By No Comments | Post a Comment

INTRODUCTION

Tranzyme Pharma is one of dozens of drug development companies in North Carolina’s Research Triangle area, a biotech hot spot that is ranked third in the nation by number of companies. The Durham company has diligently advanced therapies based on a hormone that was discovered a decade ago, a technology also used by two rivals. Now, Tranzyme’s Board of Directors has to decide how to pay for the final development step and get its drugs to market: Go public, sell the company or go back to its investors hat in hand one more time.

This is the first part of three.

Read more…