Jobs

Postdoctoral position is immediately available to study nutrient sensing by the targets of the immunosuppressant drug rapamycin: the TOR kinase homologs. Previous experience with yeast as a model system and/or signal transduction mechanisms, gene expression analysis by microarray preferable. 
 
Recent publications:
Puria, Rekha, Zurita-Martinez, S.A., and Cardenas, M.E. (2008). Nuclear translocation of Gln3 in response to nutrient signals requires Golgi to endosome trafficking in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA. 105:7194-7199. "with special commentary at PNAS and Science Signaling"
 
Puria, R. and Cardenas, M.E. (2008). Rapamycin bypasses vesicle-mediated signaling events to activate Gln3 in Saccharomyces cerevisiae. Commun. & Integrat. Biol. In press.
 
Rohde, J.R., Bastidas, R., Puria, Rekha, and Cardenas, M.E. (2008). Nutritional control via Tor signaling in Saccharomyces cerevisiae. Curr. Opin. Microbiol. 11:153-160.
 
Bastidas, R.J., Reedy, J.L., Morales-Johansson, Heitman, J., and Cardenas, M.E. (2008). Signaling cascades as drug targets in model and pathogenic fungi. Curr. Opin. Invest. Drugs. 9:856-864.
 
Rutherford, J.C., Chua, G., Hughes, T., Cardenas, M.E., and Heitman J. (2008) A Mep2- dependent transcriptional profile links permease function to gene esxpression during pseudohyphal growth in Saccharomyces cerevisiae. Mol. Biol. Cell. 19:3028-3039.
 
*Zurita-Martinez, S.A., *Puria, Rekha, Pan, X., Boeke, J.D., and Cardenas, M.E. (2007). Efficient Tor signaling requires a functional Class C Vps protein complex in Saccharomyces cerevisiae. Genetics 107, 2139-2150. *co-first authors
 
Bahn, Y-S., Xue, C., Idnurm, A., Rutherford, J.C., Heitman, J., and Cardenas, M.E. (2007). Sensing the environment: lessons from fungi. Nat. Rev. Microbiol. 5:57-69.