Posts Tagged ‘obesity’

Sabine Vollmer

Digging for the roots of diabetes

Wednesday, December 9, 2009, 7:58 pm By Sabine Vollmer

Every year, the number of Americans with diabetes rises by about 1 million and genetic risk factors alone can be blamed for only a small portion of the cases. The 30 to 35 known diabetes genes, as researchers have dubbed them, account for only about 10 percent of the risk that a brother or sister of a diabetic will also develop the disease.

Dr. Ronald Kahn

Dr. Ronald Kahn

To better understand the other 90 percent, said Dr. Ronald Kahn, a Harvard University medical professor and vice chairman of the Joslin Diabetes Center, “we have to look at the environment.” Read more…

Sabine Vollmer

Next: A crucial decision

Thursday, September 3, 2009, 8:23 am By Sabine Vollmer

This is the last part. Continued from part 2.

Developing medicines is a minefield that Tranzyme Pharma has navigated well so far. But the Durham company is about to embark on one of its trickiest missions.

Read more…

Sabine Vollmer

Getting a ghrelin drug to market

Thursday, September 3, 2009, 8:20 am By Sabine Vollmer

This is the second part of three. Continued from part 1.

Work on promising ghrelin medicines has gotten to a critical stage a decade after Japanese researchers discovered the hormone that stimulates hunger and is linked to insulin production.

Read more…

Sabine Vollmer

Ghrelin: A new hormone is found

Thursday, September 3, 2009, 8:15 am By Sabine Vollmer

INTRODUCTION

Tranzyme Pharma is one of dozens of drug development companies in North Carolina’s Research Triangle area, a biotech hot spot that is ranked third in the nation by number of companies. The Durham company has diligently advanced therapies based on a hormone that was discovered a decade ago, a technology  also used by two rivals. Now, Tranzyme’s Board of Directors has to decide how to pay for the final development step and get its drugs to market: Go public, sell the company or go back to its investors hat in hand one more time.

This is the first part of three.

Read more…

Sabine Vollmer

Next: A crucial decision

Tuesday, July 28, 2009, 9:14 am By Sabine Vollmer

This is the last part. Continued from part 2.

Developing medicines is a minefield that Tranzyme Pharma has navigated well so far. But the Durham company is about to embark on one of its trickiest missions.

Read more…

Sabine Vollmer

Getting a ghrelin drug to market

Tuesday, July 14, 2009, 11:38 am By Sabine Vollmer

This is the second part of three. Continued from part 1.

Work on promising ghrelin medicines has gotten to a critical stage a decade after Japanese researchers discovered the hormone that stimulates hunger and is linked to insulin production.

Read more…

Sabine Vollmer

Ghrelin: A new hormone is found

Monday, July 6, 2009, 9:24 am By Sabine Vollmer

INTRODUCTION

Tranzyme Pharma is one of dozens of drug development companies in North Carolina’s Research Triangle area, a biotech hot spot that is ranked third in the nation by number of companies. The Durham company has diligently advanced therapies based on a hormone that was discovered a decade ago, a technology  also used by two rivals. Now, Tranzyme’s Board of Directors has to decide how to pay for the final development step and get its drugs to market: Go public, sell the company or go back to its investors hat in hand one more time.

This is the first part of three.

Read more…